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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">agronauka</journal-id><journal-title-group><journal-title xml:lang="ru">Аграрная наука Евро-Северо-Востока</journal-title><trans-title-group xml:lang="en"><trans-title>Agricultural Science Euro-North-East</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-9081</issn><issn pub-type="epub">2500-1396</issn><publisher><publisher-name>FARC North-East</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.30766/2072-9081.2023.24.3.487-497</article-id><article-id custom-type="elpub" pub-id-type="custom">agronauka-1375</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ: ВЕТЕРИНАРНАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ОRIGINAL SCIENTIFIC ARTICLES: VETERINARY MEDICINE</subject></subj-group></article-categories><title-group><article-title>Патогенетические закономерности развития респираторных и гастроинтестинальных патологий у телят с предшествовавшей дисфункцией преджелудков в анамнезе</article-title><trans-title-group xml:lang="en"><trans-title>Pathogenetic development patterns of respiratory and gastrointestinal pathologies in calves with proventriculus dysfunction history</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0650-0837</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Попова</surname><given-names>О. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Popova</surname><given-names>O. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Попова Ольга Сергеевна, кандидат вет. наук, доцент кафедры фармакологии и токсикологии</p><p>ул. Черниговская, д. 5, г. Санкт-Петербург, Российская Федерация, 196084</p><p>secretary@spbguvm.ru</p></bio><bio xml:lang="en"><p>Olga S. Popova, PhD in Veterinary Science, associate professor at the Department of Pharmacology and Toxicology</p><p>Chernihiv str., 5, St. Petersburg, Russian Federation, 196084 </p></bio><email xlink:type="simple">alef_z@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0666-7722</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алехин</surname><given-names>Ю. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Alеkhin</surname><given-names>Yu. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алехин Юрий Николаевич, доктор вет. наук, главный научный сотрудник отдела экспериментальной терапии</p><p>ул. Ломоносова, 114б, г. Воронеж, Российская Федерация, 394087</p></bio><bio xml:lang="en"><p>Yuri N. Alеkhin, DSc in Veterinary Science, chief researcher, the Department of Experimental Therapy</p><p>Lomonosov str., 114b, Voronezh, Russian Federation, 394087 </p></bio><email xlink:type="simple">vnivipat@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8790-0540</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Паршин</surname><given-names>П. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Parshin</surname><given-names>P. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Паршин Павел Андреевич, доктор вет. наук, профессор, директор</p><p>ул. Ломоносова, 114б, г. Воронеж, Российская Федерация, 394087</p></bio><bio xml:lang="en"><p>Pavel A. Parshin, DSc in Veterinary Science, professor, Director </p><p>Lomonosov str., 114b, Voronezh, Russian Federation, 394087 </p></bio><email xlink:type="simple">vnivipat@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1673-9892</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лядова</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lyadova</surname><given-names>L. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лядова Людмила Викторовна, кандидат с.-х. наук, ведущий научный сотрудник отдела клинико-лабораторных исследований</p><p>ул. Ломоносова, 114б, г. Воронеж, Российская Федерация, 394087</p></bio><bio xml:lang="en"><p>Lyudmila V. Lyadova, PhD in Agricultural Science, leading researcher, the Department of Clinical and Laboratory Research </p><p>Lomonosov str., 114b, Voronezh, Russian Federation, 394087 </p></bio><email xlink:type="simple">vnivipat@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4794-6026</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лебедева</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Lebedeva</surname><given-names>A. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лебедева Анастасия Юрьевна, младший научный сотрудник отдела клинико-лабораторных исследований</p><p>ул. Ломоносова, 114б, г. Воронеж, Российская Федерация, 394087</p></bio><bio xml:lang="en"><p>Anastasia Yu. Lebedeva, junior researcher, the Department of Clinical and Laboratory Research </p><p>Lomonosov str., 114b, Voronezh, Russian Federation, 394087 </p></bio><email xlink:type="simple">vnivipat@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Санкт-Петербургский государственный университет ветеринарной медицины»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saint Petersburg State University of Veterinary Medicine</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБНУ «Всероссийский научно-исследовательский ветеринарный институт патологии, фармакологии и терапии»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>All-Russian Veterinary Research Institute of Pathology, Pharmacology and Therapy</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>28</day><month>06</month><year>2023</year></pub-date><volume>24</volume><issue>3</issue><fpage>487</fpage><lpage>497</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Попова О.С., Алехин Ю.Н., Паршин П.А., Лядова Л.В., Лебедева А.Ю., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Попова О.С., Алехин Ю.Н., Паршин П.А., Лядова Л.В., Лебедева А.Ю.</copyright-holder><copyright-holder xml:lang="en">Popova O.S., Alеkhin Y.N., Parshin P.A., Lyadova L.V., Lebedeva A.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.agronauka-sv.ru/jour/article/view/1375">https://www.agronauka-sv.ru/jour/article/view/1375</self-uri><abstract><p>В условиях агропромышленного комплекса, специализирующегося на интенсивном откорме молодняка крупного рогатого скота, был проведен опыт по изучению закономерностей развития респираторных и гастроинтестинальных патологий у телят с предшествовавшей дисфункцией преджелудков в анамнезе. Объектом исследований служили телята в возрасте 120 суток, которых распределили на три группы: контрольная и две подопытные, которым в рацион добавляли фитосорбент. В рацион входили сено злаковое и комбикорма (СП 21,5 %) согласно нормам и режиму кормления для животных данного возраста. Выявлено, что сокращение периода приучения телят к потреблению большого количества концентратов, оказало негативное влияние на сократительную функцию рубца и процессы пищеварения в его полости с формированием комплекса симптомов пенистой тимпании и ацидоза рубца. После курса соответствующего лечения специфические признаки указанных патологий рубца исчезли, но сохранился дисбаланс между депрессией симбионтного и активацией полостного пищеварения с формированием постоянного предпорогового уровня локальной аутоинтоксикации. Перевод животных на технологический рацион активизировал процессы метаболизма в рубце и усиления биохимического дисбаланса, что стало причиной прогрессирования синдрома эндогенной интоксикации и вегетативной дистонии с соответствующим увеличением риска развития респираторных и гастроинтестинальных патологий. Применение комбинированного нативного премикса на основе энтеросорбента на фоне остаточных патологических явлений после дисфункций преджелудков снизило уровень токсических веществ в рубце, что исключило генерализацию аутоинтоксикации при повышении функциональной нагрузки на органы пищеварения. В результате был нивелирован механизм формирования патогенетической интеграции (предрасположенности) в организме, что стало причиной снижения уровня заболеваемости животных в 6,7 раза и на 22,9 % активизации их роста.</p></abstract><trans-abstract xml:lang="en"><p>An experiment was conducted in the conditions of an industrial complex specializing in the intensive fattening of young cattle, to study the development patterns of respiratory and gastrointestinal pathologies in calves with a history of previous proventriculus dysfunction. The object of the research were calves aged 120 days, which were divided into three groups: control, and two experimental groups - with a difference in using or the absence of phytosorbent. The diet included cereal hay and compound feed (CP 21.5%) according to the norms and regimen of feeding, for animals of this age. It appeared that for calves shortening of the adaptation period to the consumption of a large amount of compound feed had a negative impact on the rumen contractile function and the processes of digestion in it with the formation of a complex of symptoms of frothy tympany and rumen acidosis. After a course of appropriate treatment, the specific symptoms of these pathologies of the rumen disappeared, but the imbalance between the depression of symbiotic and activation of abdominal digestion remained, with the formation of a constant pre-threshold level of local autointoxication. The transfer of animals to the technological diet activated the processes of rumen metabolism and increased biochemical imbalance, which caused the progression of the endogenous intoxication syndrome and vegetative dystonia with a corresponding increase in the risk of developing respiratory and gastrointestinal pathologies. The use of a combined native premix based on the enterosorbent Rigatirin against the background of residual pathological phenomena after proventriculus dysfunctions reduced the level of toxic substances in the rumen, which excluded the generalization of autointoxication with an increase in the functional load on the digestive organs. As a result, the mechanism of pathogenetic integration (predisposition) formation in the body was leveled with a corresponding decrease in the incidence of the lungs, rumen and intestines. As a result, the mechanism of pathogenetic integration (predisposition) formation in the body was leveled, which caused a 6.7-fold decrease in the level of morbidity in animals and a 22.9 % increase in their growth.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рубец</kwd><kwd>пневмонии</kwd><kwd>энтеросорбент</kwd><kwd>эндогенная интоксикация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>rumen</kwd><kwd>pneumonia</kwd><kwd>enterosorbent</kwd><kwd>endogenous intoxication</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Kostenko O.V. Russian beef sector: economic analysis and forecast. IOP Conference Series: Earth and Environmental Science. 2021;941:012010. DOI: https://doi.org/10.1088/1755-1315/941/1/012010</mixed-citation><mixed-citation xml:lang="en">Kostenko O.V. Russian beef sector: economic analysis and forecast. IOP Conference Series: Earth and Environmental Science. 2021;941:012010. DOI: https://doi.org/10.1088/1755-1315/941/1/012010</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Манжурина О. А., Пархоменко Ю. С., Перепелкина И. С., Семенова Е. В., Копытина К. О., Рожкова И. Н., Дмитриева Н. А. Этиологическая структура пневмоэнтеритов телят в хозяйствах центрального региона Российской Федерации. Ветеринарный фармакологический вестник. 2020;(1(10)):96-100. DOI: https://doi.org/10.17238/issn2541-8203.2020.1.96 EDN: PIHYQN</mixed-citation><mixed-citation xml:lang="en">Manzhurina O. A., Parkhomenko Yu. S., Perepelkina I. S., Semenova E. V., Kopytina K. O., Rozhkova I. N., Dmitrieva N. A. Etiological structure of pneumoenteritises in calves on cattle breeding farms in the central region of the Russian Federation. Veterinarnyy farmakologicheskiy vestnik = Bulletin of veterinary pharmacology. 2020;(1(10)):96-100. (In Russ.). DOI: https://doi.org/10.17238/issn2541-8203.2020.1.96</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Wilson D. J., Habing G., Winder C. B., Renaud D. L. A scoping review of neonatal calf diarrhea case definitions. Preventive Veterinary Medicine. 2023;211:105818. DOI: https://doi.org/10.1016/j.prevetmed.2022.105818</mixed-citation><mixed-citation xml:lang="en">Wilson D. J., Habing G., Winder C. B., Renaud D. L. A scoping review of neonatal calf diarrhea case definitions. Preventive Veterinary Medicine. 2023;211:105818. DOI: https://doi.org/10.1016/j.prevetmed.2022.105818</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Booker C. W., Lubbers B. V. Bovine Respiratory Disease Treatment Failure: Impact and Potential Causes. Veterinary Clinics of North America: Food Animal Practice. 2020;36(2):487-496. DOI: https://doi.org/10.1016/j.cvfa.2020.03.007</mixed-citation><mixed-citation xml:lang="en">Booker C. W., Lubbers B. V. Bovine Respiratory Disease Treatment Failure: Impact and Potential Causes. Veterinary Clinics of North America: Food Animal Practice. 2020;36(2):487-496. DOI: https://doi.org/10.1016/j.cvfa.2020.03.007</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Smith R. A., Step D. L., Woolums A. R. Bovine Respiratory Disease: Looking Back and Looking Forward, What Do We See? Veterinary Clinics of North America: Food Animal Practice. 2020;36(2):239-251. DOI: https://doi.org/10.1016/j.cvfa.2020.03.009</mixed-citation><mixed-citation xml:lang="en">Smith R. A., Step D. L., Woolums A. R. Bovine Respiratory Disease: Looking Back and Looking Forward, What Do We See? Veterinary Clinics of North America: Food Animal Practice. 2020;36(2):239-251. DOI: https://doi.org/10.1016/j.cvfa.2020.03.009</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Zhukov M., Alekhin Yu., Kalyuzhny I., Dorozhkin V., Stekolnikov A. Reasons for cattle retirement on feeding farms. BIO Web of Conferences. International Scientific-Practical Conference “Agriculture and Food Security: Technology, Innovation, Markets, Human Resources” (FIES 2019). 2020;17:0098. DOI https://doi.org/10.1051/bioconf/20201700098</mixed-citation><mixed-citation xml:lang="en">Zhukov M., Alekhin Yu., Kalyuzhny I., Dorozhkin V., Stekolnikov A. Reasons for cattle retirement on feeding farms. BIO Web of Conferences. International Scientific-Practical Conference “Agriculture and Food Security: Technology, Innovation, Markets, Human Resources” (FIES 2019). 2020;17:0098. DOI https://doi.org/10.1051/bioconf/20201700098</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Pažout V., Strakova E., Suchý P., Hygiene A. Effect of intensive fattening of bulls based on a high-grain diet on growth intensity and biochemical and acid-base parameters of blood. Czech Journal of Animal Science. 2005;50(8):355-361. DOI: http://dx.doi.org/10.17221/4177-CJAS</mixed-citation><mixed-citation xml:lang="en">Pažout V., Strakova E., Suchý P., Hygiene A. Effect of intensive fattening of bulls based on a high-grain diet on growth intensity and biochemical and acid-base parameters of blood. Czech Journal of Animal Science. 2005;50(8):355-361. DOI: http://dx.doi.org/10.17221/4177-CJAS</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Magrin L., Gottardo F., Contiero B., Cozzi G. Association between gastrointestinal tract, claw disorders, on-farm mortality and feeding management in veal calves. Italian Journal of Animal Science. 2021;20(1):6-13. DOI: https://doi.org/10.1080/1828051X.2020.1863868</mixed-citation><mixed-citation xml:lang="en">Magrin L., Gottardo F., Contiero B., Cozzi G. Association between gastrointestinal tract, claw disorders, on-farm mortality and feeding management in veal calves. Italian Journal of Animal Science. 2021;20(1):6-13. DOI: https://doi.org/10.1080/1828051X.2020.1863868</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Попова О. С., Барышев В. А. Оценка токсичности на лабораторных животных ригатирина и фитосорбционного комплекса с хитозаном. Инновационная деятельность науки и образования в агропромышленном производстве: мат-лы Международ. научно-практ. конф. Курск: КГСХА им. И. И. Иванова, 2019. С. 324-328. Режим доступа: https://elibrary.ru/item.asp?id=39223608&amp;ysclid=li1bu44idh968648866 EDN: GOYPPI</mixed-citation><mixed-citation xml:lang="en">Popova O. S., Baryshev V. A. Evaluation of toxicity of rigatirin and phytosorption complex with chitosan on laboratory animals. Innovative activity of science and education in agro-industrial production: Proceedings of International. scientific and practical. conf. Kursk: KGSKhA im. I. I. Ivanova, 2019. С. 324-328. URL: https://elibrary.ru/item.asp?id=39223608&amp;ysclid=li1bu44idh968648866</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Попова О. С., Барышев В. А. Изучение влияния Ригатирина на биохимический статус лактирующих коров. Международный ветеринарный вестник. 2019;(3):40-44. Режим доступа: https://elibrary.ru/item.asp?id=41138484&amp;ysclid=li1bwu305w942962885 EDN: QUPHZT</mixed-citation><mixed-citation xml:lang="en">Popova O. S., Baryshev V. A. Study of the influence of Rigatirin on the biochemical status of lacting cows. Mezhdunarodnyy veterinarnyy vestnik. 2019;(3):40-44. (In Russ.). URL: https://elibrary.ru/item.asp?id=41138484&amp;ysclid=li1bwu305w942962885</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Алехин Ю. Н., Жуков М. С. Способ диагностики нарушений рубцового пищеварения у жвачных: пат. №2565412 Российская Федерация. № 2014137684/15; заявл. 17.09.2014; опубл. 20.10.2015. Бюл. № 29. 12 с. Режим доступа: https://www1.fips.ru/registers-doc-view/fips_servlet?DB=RUPAT&amp;rn=4993&amp;DocNumber=2565412&amp;TypeFile=pdf</mixed-citation><mixed-citation xml:lang="en">Alekhin Yu. N., Zhukov M. S. Method for diagnosing cicatricial digestion disorders in ruminants: Patent RF, no. №2565412. 2015. URL: https://www1.fips.ru/registers-docview/fips_servlet?DB=RUPAT&amp;rn=4993&amp;DocNumber=2565412&amp;TypeFile=pdf</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Dias Batista L. F., Norris A. B., Adams J. M., Hairgrove T. B., Tedeschi L. O. Technical Note: The comparison of pH and redox potential in different locations in the reticulo-rumen of growing beef steers supplemented with different levels of quebracho extract. Journal of Animal Science. 2021;99(10):skab260. DOI: https://doi.org/10.1093/jas/skab260</mixed-citation><mixed-citation xml:lang="en">Dias Batista L. F., Norris A. B., Adams J. M., Hairgrove T. B., Tedeschi L. O. Technical Note: The comparison of pH and redox potential in different locations in the reticulo-rumen of growing beef steers supplemented with different levels of quebracho extract. Journal of Animal Science. 2021;99(10):skab260. DOI: https://doi.org/10.1093/jas/skab260</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Srivastava R., Singh P., Tiwari S., Mishra D. B., Kumar G. Sub-acute ruminal acidosis: Understanding the pathophysiology and management with exogenous buffers. Journal of Entomology and Zoology Studies. 2021;9(2):593-599. DOI: https://doi.org/10.22271/j.ento.2021.v9.i2i.8537</mixed-citation><mixed-citation xml:lang="en">Srivastava R., Singh P., Tiwari S., Mishra D. B., Kumar G. Sub-acute ruminal acidosis: Understanding the pathophysiology and management with exogenous buffers. Journal of Entomology and Zoology Studies. 2021;9(2):593-599. DOI: https://doi.org/10.22271/j.ento.2021.v9.i2i.8537</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Nagaraja T. G. Ruminal microbes, microbial products, and systemic inflammation. Journal of Animal Science. 2016;94(suppl_5):90-94. DOI: https://doi.org/10.2527/jam2016-0186</mixed-citation><mixed-citation xml:lang="en">Nagaraja T. G. Ruminal microbes, microbial products, and systemic inflammation. Journal of Animal Science. 2016;94(suppl_5):90-94. DOI: https://doi.org/10.2527/jam2016-0186</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Mizera L., Boehm K., Duckheim M., Groga-Bada P., Gawaz M., Zuern Ch. S., Eick Ch. Autonomic nervous system activity for risk stratification of emergency patients with pneumonia. The Journal of Emergency Medicine. 2018;55:472-480. DOI: https://doi.org/10.1016/j.jemermed.2018.06.016</mixed-citation><mixed-citation xml:lang="en">Mizera L., Boehm K., Duckheim M., Groga-Bada P., Gawaz M., Zuern Ch. S., Eick Ch. Autonomic nervous system activity for risk stratification of emergency patients with pneumonia. The Journal of Emergency Medicine. 2018;55:472-480. DOI: https://doi.org/10.1016/j.jemermed.2018.06.016</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Жуков М. С., Алехин Ю. Н., Моргунова В. И., Никоненко Г. В. Критерии оценки тяжести течения бронхопневмонии у телят. Ветеринарный фармакологический вестник. 2022;(2(19)):103-122. DOI: https://doi.org/10.17238/issn2541-8203.2022.2.103 EDN: XWRZRY</mixed-citation><mixed-citation xml:lang="en">Zhukov M. S., Alekhin Yu. N., Morgunova V. I., Nikonenko G. V. Kriterii otsenki tyazhesti techeniya bronkhopnevmonii u telyat. Veterinarnyy farmakologicheskiy vestnik = Bulletin of veterinary pharmacology. 2022;(2(19)):103-122. (In Russ.). DOI: https://doi.org/10.17238/issn2541-8203.2022.2.103</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
