agronaukaАграрная наука Евро-Северо-ВостокаAgricultural Science Euro-North-East2072-90812500-1396FARC North-East10.30766/2072-9081.2024.25.4.691-699agronauka-1728Research ArticleОРИГИНАЛЬНЫЕ СТАТЬИ: ВЕТЕРИНАРНАЯ МЕДИЦИНАОRIGINAL SCIENTIFIC ARTICLES: VETERINARY MEDICINEОценка гормонального и антиоксидантного статуса организма овец разных возрастных группAssessment of the hormonal and antioxidant status of the sheep of different age groupshttps://orcid.org/0000-0002-0520-7022БоголюбоваН. В.BogolyubovaN. V.

Боголюбова Надежда Владимировна, доктор биол. наук, ведущий научный сотрудник, заведующий отдела физиологии и биохимии сельскохозяйственных животных

д. 60, пос. Дубровицы, г. о. Подольск, Московская область, 142132

Nadezhda V. Bogolyubova, DSc in Biological Science, leading researcher, Head of the Department of Physiology and Biochemistry of Agricultural Animals

Dubrovitsy, 60, Podolsk Municipal District, Moscow Region, 142132

ФГБНУ «Федеральный исследовательский центр животноводства – ВИЖ имени академика Л. К. Эрнста»РоссияFederal Research Center for Animal Husbandry named after Academy Member L. K. ErnstRussian Federation202431082024254691–699Copyright © Боголюбова Н.В., 20242024Боголюбова Н.В.Bogolyubova N.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.agronauka-sv.ru/jour/article/view/1728

Цель данного исследования – изучение некоторых показателей антиоксидантного и гормонального статуса в организме овцематок и молодняка овец романовской породы, а также выявление корреляций между изученными индикаторами. Эксперимент проведен в условиях физиологического двора ФГБНУ ФИЦ ВИЖ им. Л. К. Эрнста в 2022 году в весенний период при стойловом содержании, на 2 группах овцематок (через 30 дней, n = 15 и 90 дней после окота, n = 14) и 3 группах молодняка романовской породы (в возрасте 1 месяца, n = 15; 3 месяцев, n = 14; 4 месяцев, n = 13). В крови определены показатели антиоксидантного и гормонального статуса. Математическую и статистическую обработку результатов проводили с использованием методов описательной статистики, однофакторного дисперсионного, корреляционного анализа. Высокий уровень общего антиоксидантного статуса в крови овцематок через 3 месяца после окота (2,38 мМ/л) указывает на успешную адаптацию к окислительному стрессу и накоплению ПОЛ путем использования антиоксидантов ферментативного и неферментативного звена. В крови ягнят при отъеме наблюдается максимальное накопление ТБК-АП по сравнению с животными в месячном возрасте (3,49 против 3,21 мкМ/л при р≤0,05), что компенсируется организмом за счет повышения уровня церулоплазмина и каталазного числа. В более старшем возрасте организм проявляет адекватную адаптацию к послеотъемному стрессу, что проявляется в снижении уровня ТБК-АП на 24,93 % (р≤0,05), повышении концентрации церулоплазмина, снижении активности пероксидазы (на 28,47 % при р≤0,001 и 8,13 % по сравнению с возрастом 1 и 3 месяца соответственно), повышении соотношения ТБК-АП/ЦП. Полученные знания о возрастных и физиологических изменениях показателей ПОЛ, АОЗ и гормонального статуса будут полезны при оценке состояния здоровья и помогут оказанию своевременных профилактических мероприятий, повышающих адаптивные возможности организма овец и наиболее полной реализации генетического потенциала продуктивности.

The purpose of the research was to study some indicators of antioxidant and hormonal status in the body of ewes and young sheep of the Romanov breed, as well as to identify correlations between the studied indicators. The experiment was carried out in the physiological yard of the L.K. Ernst Federal Research Center for Animal Husbandry in spring of 2022 with stall housing, on 2 groups of ewes (30 days, n = 15 and 90 days after lambing, n = 14) and 3 groups of young Romanov breed (aged 1, n = 15, 3, n = 14 and 4 months, n = 13). Indicators of antioxidant and hormonal status were determined in the blood. Mathematical and statistical processing of the results was carried out using methods of descriptive statistics, one-way analysis of variance, and correlation analysis. The high level of total antioxidant status in the blood of ewes 3 months after lambing (2.38 mmol/l) indicates successful adaptation to oxidative stress and LPO accumulation through the use of enzymatic and non-enzymatic antioxidants. In the blood of lambs upon weaning, the maximum accumulation of TBA-AP is observed compared to animals at one month of age (3.49 versus 3.21 μM/l at p≤0.05), which is compensated by the body by increasing the level of ceruloplasmin and catalase number. At an older age, the body shows adequate adaptation to post-weaning stress, which is manifested in a decrease in the level of TBA-AP by 24.93 % (p≤0.05), an increase in the concentration of ceruloplasmin, a decrease in peroxidase activity (by 28.47 % at p≤0.001 and 8.13 %, compared with the age of 1 and 3 months, respectively), increasing the TBA-AP/CP ratio. The acquired knowledge about age-related and physiological changes in LPO, AOD and hormonal status will be useful in assessing the health status and will help to provide timely preventive measures that increase the adaptive capabilities of the sheep’s body and the fullest realization of the genetic potential of productivity.

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The authors declare that there are no conflicts of interest present.