Schmallenberg disease: literature review and epizootic situation in the world and in Russia
https://doi.org/10.30766/2072-9081.2022.23.1.7-15
Abstract
Schmallenberg disease is a relatively new viral disease of ruminants that is transmitted by bloodsucking anthropods. The causative agent of Schmallenberg disease is an RNA virus with three genomic segments. The virus is resistant to frequent mutations. Ruminants, especially sheep, cows and goats are susceptible to the disease. First, Schmallenberg disease was reported in Germany in August 2011. In 2012-2013, the infection spread to the most part of Northwestern Europe. Insect vectors were the main mechanism for the spread of the disease. The spread of the disease over long distances was due to the movement of infected breeding cattle. It was in this way that the disease was introduced to Russia in 2012. Consequently, the disease has a high cross-border potential, especially if veterinary rules for the import of imported livestock are not followed. The disease can have a high incidence, but it is characterized by low mortality. The main economic losses include a decrease in productivity, abortions, and disturbances in the process of animal reproduction. Disease control is effectively implemented through vaccination and general quarantine and preventive measures.
Supporting agencies: the research was carried out under the support of the Ministry of Science and Higher Education of the Russian Federation within the state assignment (theme No. FGNM-0451-2021-0004). The authors thank the reviewers for their contribution to the peer review of this work.
About the Authors
O. A. Burova
Federal Research Center for Virology and Microbiology, Branch in Nizhny Novgorod
Russian Federation
Russian Federation
Deputy Group Leader
Veterinarnaya st., 3, Nizhny Novgorod, Russian Federation
O. I. Zakharova
Federal Research Center for Virology and Microbiology, Branch in Nizhny Novgorod
Russian Federation
Russian Federation
researcher
Veterinarnaya st., 3, Nizhny Novgorod, Russian Federation
N. N. Toropova
Federal Research Center for Virology and Microbiology, Branch in Nizhny Novgorod
Russian Federation
Russian Federation
microbiologist
Veterinarnaya st., 3, Nizhny Novgorod, Russian Federation
E. A. Liskova
Federal Research Center for Virology and Microbiology, Branch in Nizhny Novgorod
Russian Federation
Russian Federation
PhD in Veterinary Science, leading researche
Veterinarnaya st., 3, Nizhny Novgorod, Russian Federation
I. V. Yashin
Federal Research Center for Virology and Microbiology, Branch in Nizhny Novgorod
Russian Federation
Russian Federation
PhD in Biological Science, Director of the Branch
Veterinarnaya st., 3, Nizhny Novgorod, Russian Federation
A. A. Blokhin
Federal Research Center for Virology and Microbiology, Branch in Nizhny Novgorod
Russian Federation
Russian Federation
PhD in Veterinary Science, leading researcher
Veterinarnaya st., 3, Nizhny Novgorod, Russian Federation
References
1. Conraths F. J., Peters M., Beer M. Schmallenberg virus, a novel orthobunyavirus infection in ruminants in Europe: potential global impact and preventive measures. New Zealand Veterinary Journal. 2013;61(2):63-67. DOI: https://doi.org/10.1080/00480169.2012.738403
2. Saeed M. F., Li L., Wang H., Weaver S. C., Barrett A. D. Phylogeny of the Simbu serogroup of the genus Bunyavirus. Journal of General Virology. 2001;82(9):2173-2181. DOI: https://doi.org/10.1099/0022-1317-82-9-2173
3. European Food Safety Authority (EFSA). Schmallenberg virus: State of art. EFSA Journal. 2014;12(5):3681. DOI: https://doi.org/10.2903/j.efsa.2014.3681
4. Sprygin A. V., Kononov A. V., Babin Yu. Yu., Mishchenko V. A. Bolezn' Shmallenberga: molekulyarnobiologicheskie osobennosti virusa i klinicheskaya kartina (obzor). [Schmallenberg virus disease: molecular biology and clinical presentation (review)]. Sel'skokhozyaystvennaya biologiya = Agricultural Biology. 2012;47(6):24-34. (In Russ.). URL: https://www.elibrary.ru/item.asp?id=18197989
5. Sal'nikov N. I., Nikitina E. G., Zhabon E. O., Kolbasov D. V. Vyyavlenie genoma virusa Shmallenberg metodom PTsR v real'nom vremeni. [Detection of Schmallenberg virus genome by RT-PCR in real time]. Veterinariya = Veterinary. 2012;(8):57-58. (In Russ.). URL: https://www.elibrary.ru/item.asp?id=17866940
6. Hofmann M. A., Mader M., Flückiger F., Renzullo S. Genetic stability of Schmallenberg virus in vivo during an epidemic, and in vitro, when passaged in the highly susceptible porcine SK-6 cell line. Vet. Microbiol. 2015;176(1-2):97-108. DOI: https://doi.org/10.1016/j.vetmic.2015.01.010
7. Coupeau D., Claine F., Wiggers L., Kirschvink N., Muylkens B. S-segment variability during the two first years of the spread of Schmallenberg virus. Archives of Virology. 2016;161(5):1353-1358. DOI: https://doi.org/10.1007/s00705-016-2787-x
8. Izzo F., Cosseddu G. M., Polci A., Iapaolo F., Pinoni C., Dondona A.C., Valleriani F., Monaco F. Genetic characterization of Italian field strains of Schmallenberg virus based on N and NSs genes. Virus Genes. 2016;52 (4):582-585. DOI: https://doi.org/10.1007/s11262-016-1335-9
9. Vengust G., Vengust D. Z., Toplak I., Rihtaric D., Kuhar U. Post-epidemic investigation of Schmallenberg virus in wild ruminants in Slovenia. Transboundary and Emerging Diseases. 2020;67(4):1708-1715. DOI: https://doi.org/10.1111/tbed.13495
10. Caballero-Gómez J., García-Bocanegra I., Navarro N., Guerra R., Martínez-Nevado E., Soriano P., Cano-Terriza D. Zoo animals as sentinels for Schmallenberg virus monitoring in Spain. Vet. Microbiol. 2021;252:108927. DOI: https://doi.org/10.1016/j.vetmic.2020.108927
11. Mishchenko V. A. Novyy vrag. [A new enemy]. Veterinariya i zhizn' = Veterinary Medicine and Life. 2012;(4):3. (In Russ.).
12. Mouchantat S., Wernike K., Lutz W., Hoffmann B., Ulrich R. G., Börner K., Wittstatt U., Beer M. A broad spectrum screening of Schmallenberg virus antibodies in wildlife animals in Germany. Veterinary Research. 2015;46(1):99. DOI: https://doi.org/10.1186/s13567-015-0232-x
13. Rasmussen L. D., Kristensen B., Kirkeby C., Rasmussen T. B., Belsham G. J., Bødker R., Bøtner A. Culicoids as vectors of Schmallenberg virus. Emerging Infectious Diseases. 2012;18(7):1204-1206. DOI: https://doi.org/10.3201/eid1807.120385
14. Wernike K., Holsteg M., Schirrmeier H., Hoffmann B., Beer M. Natural Infection of Pregnant Cows with Schmallenberg Virus–A Follow-Up Study. PLoS ONE. 2014;9(5):e98223. DOI: https://doi.org/10.1371/journal.pone.0098223
15. Schulz C., Wernike K., Beer M., Hoffmann B. Infectious Schmallenberg Virus from Bovine Semen, Germany. Emerging Infectious Diseases. 2014;20(2):338-339. DOI: https://doi.org/10.3201/eid2002.131436
16. Phythian C. J., Glover M. J. Highs and Lows of Lambing Time: Sheep Farmers' Perceptions of the First Outbreak of Schmallenberg Disease in South West England on Their Well-Being. Int. J. Environ. Res. Public Health. 2019;16(24):5057. DOI: https://doi.org/10.3390/ijerph16245057
17. Kukharkina O. V., Borisova O. A. Bolezn' Shmallenberga: obzor literatury. [Schmallenberg disease: literature review]. Vladimir, 2014. 69 p.
18. Yanase T., Maeda K., Kato T., Nyuta S., Kamata H., Yamakawa M., Tsuda T. The resurgence of Shamonda virus, an African Simbu group virus of the genus Orthobunyavirus, in Japan. Archives of Virology. 2005;150(2):361-369. DOI: https://doi.org/10.1007/s00705-004-0419-3
19. Zientara S., Beck C., Lecollinet S. Emerging vectorial diseases: West Nile fever, Bluetongue and Schmallenberg. Bull. Acad. Natl. Med. 2020;204(9):992-999. DOI: https://doi.org/10.1016/j.banm.2020.09.041
20. Hoffmann B., Scheuch M., Hoper D., Jungblut R., Holsteg M., Schirrmeier H., Eschbaumer M., Goller K. V., Wernike K., Fischer M., Breithaupt A., Mettenleiter T. C., Beer M. Novel orthobunyavirus in Cattle, Europe, 2011. Emerging Infectious Diseases. 2012;18(3):469-472. DOI: https://doi.org/10.3201/eid1803.111905
21. Mishchenko V. A., Sukharev O. I., Makarov V. V. «Bolezn' Shmallenberga» - novaya virusnaya infektsiya zhvachnykh. [Schmallenberg disease is a new viral infection of ruminants]. Veterinarnaya praktika. 2012;1(56):5-7. (In Russ.).
22. Sedda L., Rogers D. J. The influence of the wind in the Schmallenberg virus outbreak in Europe. Scientific Reports. 2013;3:3361. DOI: https://doi.org/10.1038/srep03361
23. Balmer S., Vögtlin A., Thür B., Büchi M., Abril C., Houmard M., Danuser J., Schwermer H. Serosurveillance of Schmallenberg virus in Switzerland using bulk tank milk samples. Preventive Veterinary Medicine. 2014;116(4):370-379. DOI: https://doi.org/10.1016/j.prevetmed.2014.03.026
24. Schmallenberg virus: Analysis of the epidemiological data and assessment of impact (Scientific report of EFSA). EFSA Journal. 2012;10(6):2768. DOI: https://doi.org/10.2903/j.efsa.2012.2768
25. Azkur A. K., Albayrak H., Risvanli A., Pestil Z., Ozan E., Yılmaz O., Tonbak S., Cavunt A., Kadı H., Macun H. C., Acar D., Ӧzenҫ E., Alrparslan S., Bulut H. Antibodies to Schmallenberg virus in domestic livestock in Turkey. Tropical Animal Health and Production. 2013;45:1825-1828. DOI: https://doi.org/10.1007/s11250-013-0415-2
26. Beer M. Conraths F. J., van der Poel W. H. Schmallenberg virus - a novel Orthobunyavirus emerging in Europe. Epidemiol. Infect. 2013;141(1):1-8. DOI: https://doi.org/10.1017/S0950268812002245
27. Simmons A. Schmallenberg virus in 2012/13. VetRecord. 2012;171(25):651–652. DOI: https://doi.org/10.1136/vr.e8629
28. Hahn K., Habierski A., Herder V., Wohlsein P., Peters M., Hansmann F., Baumgärtner W. Schmallenberg virus in central nervous system of ruminants. Emerging Infectious Diseases. 2013;19(1):154-155. DOI: https://doi.org/10.3201/eid1901.120764
29. Wernike K., Eschbaumer M., Schirrmeier H., Blohm U., Breithaupt A., Hoffmann B., Beer M. Oral exposure, reinfection and cellular immunity to Schmallenberg virus in cattle. Vet. Microbiol. 2013;165(1-2):155-159. DOI: https://doi.org/10.1016/j.vetmic.2013.01.040
30. Wernike K., Eschbaumer M., Breithaupt A., Hoffmann B., Beer M. Schmallenberg virus challenge models in cattle: Infectious serum or culture-grown virus? Veterinary Research. 2012;43:84. DOI: https://doi.org/10.1186/1297-9716-43-84
31. Roberts H., Middlemiss C., Gibbens N. Schmallenberg virus: Responding to the challenge. The Veterinary Journal. 2012;194(1):1-2. DOI: https://doi.org/10.1016/j.tvjl.2012.08.028
32. Dominguez M., Gache K., Touratier A., Perrin J-B., Fediaevsky A., Collin E., Bréard E., Sailleau C., Viarouge C., Zanella G., Zientara S., Hendrikx P., Calavas D. Spread and impact of the Schmallenberg virus epidemic in France in 2012-2013. BMC Veterinary Research. 2014;10(1):248. DOI: https://doi.org/10.1186/s12917-014-0248-x
33. Steinrigl A., Schiefer P., Schleicher C., Peinhopf W., Wodak E., Bagó Z., Schmoll F. Rapid spread and association of Schmallenberg virus with ruminant abortions and foetal death in Austria in 2012/2013. Preventive Veterinary Medicine. 2014;116(4):350-359. DOI: https://doi.org/10.1016/j.prevetmed.2014.03.006
34. Fetal deformities detected during surveillance for Schmallenberg virus. VetRecord. 2012;171(5):117-120. DOI: https://doi.org/10.1136/vr.e4828
35. Varela M., Schnettler E., Caporale M., Murgia C., Barry G., McFarlane M., McGregor E., Piras I. M., Shaw A., Lamm C., Janowicz A., Beer M., Glass M., Herder V., Hahn K., Baumgärtner W., Rohl A., Palmarini M. Schmallenberg virus pathogenesis, tropism and interaction with the innate immune system of the host. PLoS Pathogens. 2013;9(1):e1003133. DOI: https://doi.org/10.1371/journal.ppat.1003133
36. Van den Brom R., Luttikholt S., Lievaart-Peterson K., Peperkamp N., Mars M., Van Der Poel W., Vellema P. Epizootic of ovine congenital malformations associated with Schmallenberg virus infection. Tijdschr Diergeneeskd. 2012;137(2):106-111.
37. Van der Heijden H. M. J. F., Bouwstra R. J., Mars M. H., Van der Poel W. H. M., Wellenberg G. J., Van Maanen C. Development and validation of an indirect enzyme-linked immunosorbent assay for the detection of antibodies against Schmallenberg virus in blood samples from ruminants. Research in Veterinary Science. 2013;95(2):731-735. DOI: https://doi.org/10.1016/j.rvsc.2013.04.022
38. Fischer M., Schirrmeier H., Wernike K., Wegelt A., Beer M., Hoffmann B. Development of a pan-Simbu realtime reverse transcriptase PCR for the detection of Simbu serogroup viruses and comparison with SBV diagnostic PCR systems. Virology Journal. 2013;10(1):327. DOI: https://doi.org/10.1186/1743-422X-10-327
39. De Regge N., Van den Berg T., Georges L., Cay B. Diagnosis of Schmallenberg virus infection in malformed lambs and calves and first indications for virus clearance in the fetus. Veterinary Microbiology. 2013;162(2-4):595-600. DOI: https://doi.org/10.1016/j.vetmic.2012.11.029
40. Hoffmann B., Schulz C., Beer M. First detection of Schmallenberg virus RNA in bovine semen, Germany, 2012. Veterinary Microbiology. 2013;167(3-4):289-295. DOI: https://doi.org/10.1016/j.vetmic.2013.09.002
41. Tarlinton R., Daly J., Dunham S., Kydd J. The challenge of Schmallenberg virus emergence in Europe. The Veterinary Journal. 2012;194(1):10-18. DOI: https://doi.org/10.1016/j.tvjl.2012.08.017
42. Humphries D., Burr P. Schmallenberg virus milk antibody ELISA. VetRecord. 2012;171(20):511-512. DOI: https://doi.org/10.1136/vr.e7739
43. Bouchemla F., Agoltsov V. A., Larionov S. V., Popova O. M., Shvenk E. V. Epizootiological study on spatiotemporal clusters of Schmallenberg virus and Lumpy skin diseases: The case of Russia. Veterinary World. 2018;11(9):1229-1236. DOI: https://doi.org/10.14202/vetworld.2018.1229-1236
44. Claine F., Coupeau D., Wiggers L. Muylkens B., Kirschvink N. Modelling the evolution of Schmallenberg virus seroprevalence in a sheep flock after natural infection. Preventive Veterinary Medicine. 2018;154:132-138. DOI: https://doi.org/10.1016/j.prevetmed.2018.03.024
45. Wernike K., Beer M. Schmallenberg Virus: To Vaccinate, or Not to Vaccinate? Vaccines. 2020;8(2):287. DOI: https://doi.org/10.3390/vaccines8020287
46. Endalew A. D., Faburay B., Wilson W. C., Richt J. A. Schmallenberg Disease-A Newly Emerged CulicoidesBorne Viral Disease of Ruminants. Viruses. 2019;11(11):1065. DOI: https://doi.org/10.3390/v11111065
Review
For citations:
Burova O.A., Zakharova O.I., Toropova N.N., Liskova E.A., Yashin I.V., Blokhin A.A. Schmallenberg disease: literature review and epizootic situation in the world and in Russia. Agricultural Science Euro-North-East. 2022;23(1):7-15. (In Russ.) https://doi.org/10.30766/2072-9081.2022.23.1.7-15
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